All patients (n=394) | 50–70 years (n=271) | |
Demographic variables | ||
Age (years) | 54.8 (11.6) | 61.5 (6.2) |
BMI1-150(kg/m2) | 24.0 (4.2) | 24.5 (4.4) |
Menopause (%) | 66.0 | 91.9 |
Menopause age (years) | 47.9 (5.5) | 48.1 (5.4) |
Oophorectomy (%) | 4.3 | 4.8 |
Current users of oestradiol (%) | 28.5 | 35.4 |
Bisphosphonates (%) | 2.6 | 3.8 |
Smoking | ||
Non-smoker (%) | 33.0 | 30.5 |
Previous smoker (%) | 30.5 | 32.4 |
Current smoker (%) | 36.5 | 37.0 |
Disease variables | ||
Disease duration (years) | 13.0 (9.4) | 14.3 (10.2) |
Rheumatoid factor positive (%) | 52.0 | 54.3 |
Investigator's global assessment (VAS1-150 0–100 mm) | 28.7 (24.1) | 32.0 (25.3) |
Patient's global assessment (1–5) | 2.63 (0.88) | 2.72 (0.91) |
MHAQ1-150 (range 1–4) | 1.61 (0.50) | 1.70 (0.51) |
Pain (VAS 0–100 mm) | 36.1 (21.9) | 39.7 (22.0) |
Fatigue (VAS 0–100 mm) | 44.9 (27.8) | 46.4 (28.0) |
28 Swollen joint count | 7.84 (6.11) | 8.48 (6.28) |
28 Tender joint count | 6.84 (6.36) | 7.53 (6.67) |
18 Deformed joint count | 2.15 (3.70) | 2.63 (4.05) |
ESR1-150 (mm/1st h) | 21.6 (16.5) | 23.2 (17.4) |
CRP1-150 (mg/l) | 16.2 (11.9) | 16.5 (12.3) |
DAS1-150 | 4.49 (1.37) | 4.70 (1.33) |
Corticosteroids | ||
Never user (%) | 36.3 | 30.7 |
Previous user (%) | 23.2 | 23.4 |
Current user (%) | 40.5 | 46.0 |
Non-vertebral fracture (%) | 21.2 | 26.5 |
↵1-150 BMI = body mass index; VAS = visual analogue scale; MHAQ = Modified Health Assessment Questionnaire; ESR = erythrocyte sedimentation rate; CRP = C reactive protein; DAS = disease activity score.