Global CD4 counts and lining layer hyperplasia scores before and after dosing with intra-articular primatised anti-CD4 monoclonal antibody
Global | CD4 before dose | CD4 after dose | Difference in scores | Hyperplasia before dose | Hyperplasia after dose | Difference in scores | |
---|---|---|---|---|---|---|---|
Treatment groups | 0 mg | 7 | 8 | −1 | 2 | 4 | −2 |
3 | 3 | 0 | 0 | 2 | −2 | ||
Median | 5 | 5.5 | −0.5 | 1 | 3 | −2 | |
0.4 mg | 2 | 1 | 1 | 4 | 0.5 | 3.5 | |
8 | 6 | 2 | 5 | 6 | −1 | ||
4 | 7 | −3 | 2.5 | 0 | 2.5 | ||
Median | 4 | 6 | −2 | 4 | 0.5 | 3.5 | |
40 mg | 6 | 8 | −2 | 6 | 8 | −2 | |
6 | 3 | 3 | 4 | 5.5 | −1.5 | ||
1 | 0 | 1 | 3 | 1.5 | 1.5 | ||
8 | 6 | 2 | 7 | 5 | 2 | ||
5 | 3 | 2 | 3 | 2.5 | 1.5 | ||
7 | 4 | 3 | 6.5 | 2.5 | 4 | ||
2 | 3 | −1 | 1 | 1 | 0 | ||
Median | 6 | 3 | 3 | 4 | 2.5 | 1.5 |