Arthroscopic VAS assessments (mm), observer scoring overall synovitis before and after dosing with intra-articular primatised anti-CD4 monoclonal antibody
Arthroscopic VAS for synovitis before dose | Arthroscopic VAS for synovitis after dose | Difference in scores | ||
---|---|---|---|---|
Treatment groups | Placebo | 69 | 76 | 7 |
0 mg | 67 | 70 | −3 | |
median | 68 | 73 | −5 | |
0.4 mg | 64 | 60 | 4 | |
86 | 48 | 38 | ||
64 | 37 | 27 | ||
median | 64 | 48 | 27 | |
40 mg | 89 | 71 | 28 | |
80 | 58 | 22 | ||
76 | 47 | 29 | ||
93 | 41 | 52 | ||
77 | 63 | 14 | ||
83 | 73 | 10 | ||
71 | 61 | 10 | ||
median | 80 | 61 | 22 |