Table 1

Frequency of autoantibodies in patients with systemic lupus erythematosus (SLE), undifferentiated/overlap CTD (UCTD), and primary antiphospholipid syndrome (APS) and their association with anti-P antibodies. (All values are expressed as number (%))

Total
patients		Anti-P positive patientsAnti-P negative patients
SLE (n=60) (n=12) (n=48)
 Anti-dsDNA38  (63) 8 (67)30 (63)
 Anti-Sm17 (28) 2 (17)15 (31)
 Anti-nRNP23 (38) 2 (17)21 (44)
 Anti-Ro/SSA20 (33) 2 (17)18 (38)
 Anti-La/SSB 5 (8) 1 (8) 4 (8)
 IgG aCL29 (48)11 (92)1-151 18 (38)
 IgM aCL 9 (15) 3 (25) 6 (13)
 LA 4 (7) 2 (17) 2 (4)
Overlap/UCTD1-150(n=80) (n=4) (n=76)
 Anti-dsDNA13 (16) 013 (17)
 Anti-Sm 9 (11) 1 (25) 8 (11)
 Anti-nRNP50 (63) 2 (50)48 (63)
 Anti-Ro/SSA22 (28) 2 (50)20 (26)
 Anti-La/SSB 3 (4) 0 3 (4)
 Anti-Scl70 6 (8) 0 6 (8)
 Anti-Jo-1 2 (3) 0 2 (3)
 Anticentromere 4 (5) 1 (25) 3 (4)
 IgG aCL17 (46) 4 (100)13 (33)
 IgM aCL 3 (8) 0 3 (8)
 LA1-152  2 (5) 0 2 (5)
Primary APS (n=22) (n=0) (n=22)
 IgG aCL19 (86)0.019 (86)
 IgM aCL 8 (36)0.0 8 (36)
 LA14 (64)0.014 (64)

  • ↵1-150 Thirty seven of 80 patients with overlap/UCTD were concomitantly tested for antiphospholipid antibodies.

  • ↵1-151 Significant at p=0.0009, odds ratio 18.33, 95% confidence interval 2.180 to 154.2.

  • ↵1-152 LA = lupus anticoagulant.