Patient 1 | Patient 2 | ||||||||
---|---|---|---|---|---|---|---|---|---|
First infusion | Second infusion | Before | After | ||||||
Before | After | Before | After | ||||||
Proteinuria | 12.25 g/24 h | 4.2 g/24 h | 5.2 g/24 h | 12.4 g/24 h | 4 g/24 h | 7.2 g/24 h | |||
Serum creatinine | 190 μmol/l | 120 μmol/l | 154 μmol/l | 163 μmol/l | 149 μmol/l | 243 μmol/l | |||
Anti-ds DNA | 132 IU/ml | 58 IU/ml | 292 IU/ml | >300 IU/ml | 171 IU/ml | 49 IU/ml | |||
C3 | 0.51 g/l | 0.67 g/l | 0.72 g/l | 0.51 g/l | 0.39 g/l | 0.60 g/l | |||
C4 | 0.13 g/l | 0.14 g/l | 0.15 g/l | 0.12 g/l | 0.12 g/l | 0.16 g/l | |||
C3d | 22 units/ml | 10 units/ml | 23 units/ml | 20 units/ml | 13 units/ml | 12 units/ml | |||
Urine analysis | red cells, hyalogranular, cellular casts | red cells, a few casts |
Reference ranges: serum creatinine 50–100 μmol/l, anti-dsDNA: 50–300 IU/ml positive, >300 IU/ml strongly positive, C3: 0.63–1.19 g/l, C4: 0.11–0.43 g/l, C3d: up to 12 units/ml.