Epitope recognition of IgG, IgM and IgA autoantibodies to different subfragments3-150 of the Ro 52 kDa and Ro 60 kDa proteins
| Ro 52 n† | 52-4 n (%) | 52-5 n (%) | 52-6 n (%) | Ro 60 n | 60-E n (%) | 60-G n (%) | 60-K n (%) | ||
|---|---|---|---|---|---|---|---|---|---|
| SLE | IgG | 8 | 6 (75) | 0 | 6 (75) | 6 | 1 (17) | 6 (100) | 0 |
| IgM | 7 | 1 (14) | 0 | 2 (29) | 2 | 0 | 1 (50) | 0 | |
| IgA | 8 | 4 (50) | 0 | 6 (75) | 7 | 1 (14) | 4 (57) | 1 (14) | |
| pSS | IgG | 8 | 8 (100) | 0 | 8 (100) | 6 | 2 (33) | 6 (100) | 3 (50) |
| IgM | 8 | 4 (50) | 0 | 6 (75) | 6 | 0 | 3 (50) | 0 | |
| IgA | 8 | 6 (75) | 0 | 7 (88) | 6 | 3 (50) | 4 (67) | 0 |
↵3-150 The subfragments are illustrated in figure 1. †Number of patients with positive immunoblotting to full length Ro 52 kDa and Ro 60 kDa, and their subfragments, respectively.