Frequency of detectable antigen specific IgG, IgM and IgA autoantibodies in patients with SLE (n=30), pSS (n=25) and normal controls (n=20) by immunoblotting
| Antigen | Ig Class | Control (%) | SLE n (%) | pSS n (%) |
|---|---|---|---|---|
| Ro 52 | IgG | 0 | 24 (80) | 21 (84) |
| IgM | 0 | 21 (70) | 19 (76) | |
| IgA | 0 | 22 (73) | 21 (84) | |
| Ro 60 | IgG | 0 | 16 (53) | 14 (56) |
| IgM | 0 | 7 (23) | 6 (24) | |
| IgA | 0 | 14 (47) | 13 (52) | |
| La | IgG | 0 | 21 (70) | 20 (80) |
| IgM | 0 | 20 (67) | 19 (76) | |
| IgA | 0 | 20 (67) | 20 (80) | |
| MaBP | IgG | 0 | 0 | 0 |
| IgM | 0 | 0 | 0 | |
| IgA | 0 | 0 | 0 |
MaBP (Maltose binding protein) is the fusion partner for the recombinant antigens.