Enzyme activities by group and cell type
| Enzyme | Cell type | SLE | Controls | p value |
|---|---|---|---|---|
| 5′NT1-150 | PBMC | 9.4 (6.4) | 21.9 (8.3) | <0.000† |
| T cells | 10.7 (5.5) | 22.2 (6.4) | =0.001‡ | |
| B cells | 41.1 (32.6) | 56.1 (25.4) | NS | |
| HGPRT | PBMC | 7.5 (2.5) | 9.7 (3.9) | =0.03† |
| T cells | 5.5 (1.9) | 4.9 (1.9) | NS | |
| B cells | 3.8 (1.6) | 4.2 (0.9) | NS | |
| PNP | PBMC | 170 (70) | 176 (55) | NS |
| T cells | 101 (31) | 101 (36) | NS | |
| B cells | 77 (39) | 75 (19) | NS | |
| TPMT | Ery-lysate | 19.6 (4.6) | 22.6 (4.1) | =0.05‡ |
↵1-150 5′NT activities of women only. Values are means (SD). 5′NT, HGPRT, and PNP activities are in (nmol/106 viable cells/h) TPMT activity is in (pmol/106 cells/h).† t test, ‡Mann-Whitney U test, NS: not significant.