Table 1

Enzyme activities by group and cell type

EnzymeCell typeSLEControlsp value
5′NT1-150 PBMC9.4 (6.4)21.9 (8.3)<0.000
T cells10.7 (5.5)22.2 (6.4)=0.001
B cells41.1 (32.6)56.1 (25.4)NS
HGPRTPBMC7.5 (2.5)9.7 (3.9)=0.03
T cells5.5 (1.9)4.9 (1.9)NS
B cells3.8 (1.6)4.2 (0.9)NS
PNPPBMC170 (70)176 (55)NS
T cells101 (31)101 (36)NS
B cells77 (39)75 (19)NS
TPMTEry-lysate19.6 (4.6)22.6 (4.1)=0.05
  • 1-150 5′NT activities of women only. Values are means (SD). 5′NT, HGPRT, and PNP activities are in (nmol/106 viable cells/h) TPMT activity is in (pmol/106 cells/h). t test, Mann-Whitney U test, NS: not significant.