Clinical and immunological manifestations of patients with ‘primary’ SS and HCV infection compared with patients without HCV infection
|
SS with HCV infection (n=13) |
SS without HCV infection (n=77) | |
| Dry mouth | 11 (85) | 76 (99) |
| Dry eyes | 12 (92) | 72 (95) |
| Parotidomegaly | 3 (23) | 31 (40) |
| Splenomegaly | 6 (46) | 3 (4) |
| Articular involvement | 7 (54) | 36 (47) |
| Raynaud’s phenomenon | 4 (31) | 10 (13) |
| Cutaneous vasculitis | 3 (23) | 8 (10) |
| Pulmonary involvement | 1 (8) | 12 (16) |
| Hepatic involvement | 13 (100)1-150 | 5 (6) |
| Peripheral neuropathy | 3 (23) | 7 (9) |
| Autoimmune thyroiditis | 3 (23) | 9 (12) |
| Thrombocytopenia | 6 (46) | 7 (9) |
| Cryoglobulins | 6/11 (55) | 5/37 (14) |
| Hypocomplementaemia | 4 (31) | 9 (12) |
| ANA (+) | 10 (77) | 57 (74) |
| SMA (+) | 3 (23) | 22 (29) |
| AMA (+) | 2 (15) | 0 (0) |
| RF (+) | 8 (62) | 29 (38) |
| Ro-SSA (+) | 6 (46) | 22 (29) |
| La-SSB (+) | 4 (30) | 11 (14) |
↵1-150 p < 0.05. ANA = antinuclear antibodies; SMA = antismooth muscle antibodies; AMA = antimitochondrial antibodies; RF = rheumatoid factor. Figures in parentheses are percentages.