LMP2CfoI genotypes in Mexican AS patients stratified by age at onset and history of AAU
LMP2-CfoI genotype | |||
AA (%) | AB (%) | BB (%) | |
Guadalajara3-150 | |||
Juveniles | |||
AAU+ | 0 | 1 (50) | 1 (50) |
AAU− | 0 | 3 (20) | 12 (80) |
Adults | |||
AAU+ | 2 (22.2) | 2 (22.2) | 5 (55.6) |
AAU− | 2 (3.1) | 17 (26.6) | 45 (70.3) |
Mexico City3-151 | |||
Juveniles | |||
AAU+ | 2 (16.7) | 4 (33.3) | 6 (50) |
AAU− | 0 | 14 (35) | 26 (65) |
Adults | |||
AAU+ | 0 | 2 (66.7) | 1 (33.3) |
AAU− | 2 (8.0) | 5 (20) | 18 (72) |
↵3-150 Stratified exact OR = 2.12 (95% CI, 0.46, 9.24; p = 0.40).
↵3-151 Stratified exact OR = 2.27 (95% CI, 0.62, 8.54; p = 0.25).
Combined population stratified exact OR = 2.30 (95% CI, 0.90, 5.91; p = 0.087). OR = The exact conditional maximum likelihood estimates, stratified by age at onset of disease, for the odds ratio relating LMP2A allelic frequency and history of AAU.