Table 2

Histopathological and histochemical scorings of horizontal (A) and vertical (B) sections of femur. Grading according to table 1

Group123
% Acellular cartilageA2.1 (0.3)2.2 (0.4)2.0 (0.0)
B2.0 (0)2.0 (0)1.8 (1.8)
Loss of matrix (erosion)A000
B0.7 (0.8)0.8 (0.9)0.4 (0.5)
ClusteringA1.5 (0.7)2.1 (0.8)1.4 (0.8)
B1.2 (0.6)1.3 (0.9)0.9 (0.6)
PannusA0.6 (0.7)0.1 (0.3)0.1 (0.3)
B1.1 (1.0)0.8 (0.8)0.2 (0.4)
Orthochromasia (proteoglycan depletion)A1.7 (0.9)1.0 (0.8)0.2 (0.4)2-150
B1.9 (0.7)1.3 (0.8)0.2 (0.4)2-150
Severity of synovitisA2.3 (0.8)1.1 (0.9)0.3 (0.7)2-150
B2.2 (0.9)1.3 (1.1)0.6 (0.9)
Vascular elements crossing the tidemarkA0.5 (0.5)0.6 (0.5)0.5 (0.5)
B0.4 (0.5)0.5 (0.5)0.1 (0.3)
Enchondral bone marrow cavitiesA0.4 (0.5)0.4 (0.5)0.3 (0.5)
B0.3 (0.4)0.5 (0.5)0.2 (0.4)
Height of cartilageA97.6 (2.9)89.5 (5.9)90.8 (9.1)
B97.3 (5.7)91.0 (13.1)100 (0)
Total scoreA8.2 (1.9)6.5 (1.4)4.0 (1.0)2-150
B8.8 (2.5)7.4 (2.6)4.2 (2.2)2-150
  • 2-150 p<0.05 between groups 2–3. Data shown as mean (SD).