Table 1

Clinical and laboratory data in six patients with renal vein thrombosis

Patient (age)	LN	Clinical symptom	APS profile	NS	Initial renal function	Previous APS symptom	Lupus features at time of RVT diagnosis
Patient 1 (20)	Class IV AI: 13, CI: 4	Peripheral oedema	ACA 3.65, PLT: 209	(+,4m^*)	Transient GFR↓, ERPF↓	Pulmonary HT	Active lupus nephritis
		Flank soreness	RPR (−), APTT→		Creatinine↑, TP: 3.8 g
Patient 2 (30)	Class III AI: 14, CI: 5	Peripheral oedema	ACA: 56, PLT: 112 RPR (−), APTT↑	(+,4m)	BUN/Cr: normal TP: 4.1 g	Raynaud, CRAO, skin ulceration, AVN, digital gangrene		Pleural effusion, arthritis, haemolytic anaemia and vasculitis
						Raynaud, CRAO, skin ulceration, AVN, digital gangrene
Patient 3 (25)	Class V AI: 12, CI: 5	Peripheral oedema	ACA: 1.12, PLT: 349	(+,3m)	Transient GFR↓, ERPF↓	Pulmonary HT		Arthralgia, malar rash with rapid increase of proteinuria
		Flank soreness	RPR (−), APTT→		Creatinine↑, TP: 4.4 g	Pulmonary HT		Arthralgia, malar rash with rapid increase of proteinuria
Patient 4 (35)	Class V AI: 16, CI: 4	Peripheral oedema	ACA: 26.2, PLT: 75	(+,2m)	BUN/Cr: normal TP: 3.7 g	Pulmonary HT, AVN, deep vein thrombosis, repeated abortion		Digital vasculitis, fever, active lupus nephritis
			RPR (−), APTT→			Pulmonary HT, AVN, deep vein thrombosis, repeated abortion		Digital vasculitis, fever, active lupus nephritis
Patient 5 (34)	Class IV AI: 17, CI: 5	Peripheral oedema	ACA: 310, PLT: 60 RPR (+), APTT↑	(+,4m)	BUN/Cr: normal TP: 5.3 g	Repeated abortion, brain atrophy	Malar rash, pericardial effusion, haemolytic anaemia
						Old lacunar infarction	Malar rash, pericardial effusion, haemolytic anaemia
Patient 6 (39)	Class IV AI: 11, CI: 7	Peripheral oedema	ACA: 22.4, PLT: 43	(+,2m)	Cr: 6.2, Acute renal failure, TP: 4.1 g	Multiple cerebral infarction		Synovitis, fever, malar rash
			RPR (−), APTT→			Multiple cerebral infarction		Synovitis, fever, malar rash

LN: Lupus nephritis, classified according to WHO criteria; APS: antiphospholipid antibody syndrome; NS: nephrotic syndrome ; ACA: anticardiolipin antibody, IgG subclass, with normal range 15 GPL unit/ml; CRAO: central retinal artery occlusion; AVN: avascular necrosis; ↑, ↓, →: increased, decreased, and normal range, respectively; PLT: platelet count, platelet count ×10³/μl; ERPF: effective renal plasma flow, determined by scintigraphy; GFR: glomerular filtration rate; TP: 24 hours total urine protein; AI: active renal biopsy index; CI: chronic index, Cr: creatinine; RPR: rapid plasma reagin. ^*Duration of a previous nephrotic syndrome history (months) before diagnosis of renal vein thrombosis.