Table 2

TAP1 and TAP2 genotype frequencies in RA patients and normal controls

LMP genotypesPatients
(n=60) n (%)
Controls
(n=61) n (%)
Positive for shared epitopeNegative for shared epitope
Patients
(n=35) n (%)
Controls
(n=28) n (%)
Patients
(n=25) n (%)
Controls
(n=33) n (%)
TAP12-150A/A48 (80)41 (67.2)30 (85.7)18 (64.5)18 (72)23 (70)
TAP12-150A/C3 (5)1 (1.6)1 (2.9)1 (3.5)2 (8)0
TAP12-150A/D1 (1.7)3 (5)01 (3.5)1 (4)2 (6)
TAP12-150B/C1 (1.7)01 (2.9)000
TAP12-150D/D01 (1.6)0001 (3)
TAP12-150F/F01 (1.6)01 (3.5)00
TAP1 NA2-150 7 (11.6)14 (23)3 (8.5)7 (25)4 (16)7 (21)
TAP22-150A/A14 (23.4)14 (23)5 (14.3)5 (17.8)9 (36)9 (27.3)
TAP22-150A/B17 (28.4)15 (24.6)11 (31.4)8 (28.5)6 (24)7 (21.2)
TAP22-150A/C5 (8.3)5 (8.2)4 (11.4)2 (7.2)1 (4)3 (9)
TAP22-150A/D01 (1.6)01 (3.6)00
TAP22-150A/E1 (1.6)2 (3.3)1 (2.9)1 (3.6)01 (3)
TAP22-150A/F4 (6.7)6 (9.8)3 (8.6)3 (10.7)1 (4)3 (9)
TAP22-150B/B7 (11.7)5 (8.2)3 (8.6)1 (3.6)4 (16)4 (12.2)
TAP22-150B/F1 (1.6)4 (6.6)1 (2.9)2 (7.2)02 (6.1)
TAP22-150C/C1 (1.6)2 (3.3)1 (2.9)002 (6.1)
TAP22-150C/D01 (1.6)01 (3.6)00
TAP2 NA2-150 10 (16.7)6 (9.8)6 (17)4 (14.2)4 (16)2 (6.1)