Table 2

Results of methotrexate treatment in patients with adult onset Still’s disease

Patient		Response		Duration to response or adverse reaction (weeks)		Maximum dose of methotrexate (mg/week)		Total dose of methotrexate (mg)	Adverse reactions	Dose of PSL (mg/d) or DS (mg/d)
Patient		Response		Duration to response or adverse reaction (weeks)		Maximum dose of methotrexate (mg/week)		Total dose of methotrexate (mg)	Adverse reactions	Before MTX	After MTX
1	Remission	3	10	15		PSL 20	0
2	Remission	8	5	40		PSL10	10
3	Remission	8	20	120		PSL16	12.5
4	Remission	9	7.5	42.5		DS 75	DS 75
5	Remission	12	12.5	100		PSL18	8
6	Remission	12	7.5	90		DS 75	0
7	Remission	16	15	180		DS 75	0
8	Remission+AR	16	20	200	Moderate liver dysfunction	DS 75	0
9	Ineffective	12	7.5	75		DS 75	PSL pulse
10	Ineffective+AR	16	5	40	Nausea	PSL 20	PSL 30
11	Ineffective+AR	16	10	100	Mild liver dysfunction	PSL 11	PSL 15
12	Ineffective+AR	16	15	195	Acute interstitial pneumonia	DS 75	PSL pulse
13	AR	2	5	10	Severe nausea, appetite loss	PSL 10	PSL 15