Clinical features in 24 patients with rheumatoid arthritis and intractable diarrhoea caused by secondary amyloidosis
| Age at diagnosis of amyloidosis, mean (SD) y (median; range) | 57 (9) (57; 40–74) |
| Duration of arthritis at diagnosis of amyloidosis, mean (SD) y (median; range) | 13 (5) (13; 3–22) |
| Articular erosions (%) | 100 |
| Rheumatoid factor (%)* | 92 |
| Lansbury activity index mean (SD) (median; range)† | 69 (21) (79; 38–119 |
| CRP, mg/dl mean (SD) (median; range)‡ | 8.9 (5.6) (11.6; 0.6–22.5) |
| CRN, mg/dl mean (SD) (median; range)‡ | 0.6 (0.2) (0.8; 0.3–1.2) |
| Proteinuria (%) | 17 |
| Haematuria (%) | 8 |
CRP=C reactive protein; CRN=creatinine. *Rheumatoid factor in serum was measured by the rheumatoid arthritis haemagglutination test.†Patients were evaluated for four parameters (morning stiffness, grip strength, joint count, and erythrocyte sedimentation rate) at the nearest point before onset of intractable diarrhoea. ‡Values at nearest point before onset of intractable diarrhoea.