Table 3

Interferon γ and IL 10 production (mean(SD)) in whole blood from study 1 subjects after incubation with 33 μg/ml of DRβ1(0401), DRβ1(0402), E coli dnaJa (aa 56-70) or hsp40 peptides

Cytokine Peptide Cytokine production in response to peptide p Value
Control Non-RA RA
Interferon γ (U/ml) *040118.5 (16.2)8.7 (25.7)4 (16.9)NS
*040238.8 (152.4)6.0 (23.2)1.8 (7.2)NS
dnaJa10.0 (37.8)4.0 (14.9)3.5 (14.9)NS
hsp4019.6 (77.2)3.7 (14.7)1.8 (5.9)NS
IL 10 (ng/ml) *04010.05 (0.13)0.04 (0.09)0.04 (0.10)NS
*04020.05 (0.18)0.03 (0.06)0.02 (0.04)NS
dnaJa0.02 (0.06)0.03 (0.06)0.01 (0.04)NS
hsp400.02 (0.08)0.03 (0.07)0.02 (0.04)NS