Extra-articular manifestations, antinuclear antibodies, and HLA DR4 in patients with rheumatoid arthritis
| Group I (high avidity) | Group II (low avidity | P | |
| Sex ratio F/M | 30/7 | 13/7 | 0.19 |
| Raynaud’s phenomenon | 3/37 (8%) | 1/20 (5%) | 0.56 |
| Vasculitis | 2/37 (5%) | 0/20 (0%) | 0.42 |
| Nodules | 9/37 (24%) | 7/20 (35%) | 0.39 |
| Antinuclear antibodies | 14/37 (38%) | 6/20 (30%) | 0.64 |
| HLA DR4 | 26/30 (87%) | 9/11 (82%) | 0.60 |