Patient | 2-150Baseline and follow up study MR variables | |||||||
Time to maximum synovial lining signal ratio (min) | Maximum synovial lining signal ratio | Total synovial lining volume (ml) | Single slice synovial lining volume (ml) | |||||
1 | NC | CNA1 | NC | CNA1 | 97 | CNA1 | 1.96 | CNA1 |
2 | 20.7 | 3.5 | 1.7 | 2.5 | 140 | 115 | 4.16 | 3.82 |
3† | 5.0 | CNA2 | 1.3 | CNA2 | 52 | CNA2 | 1.81 | CNA2 |
4† | 20.7 | CNA2 | 2.0 | CNA2 | 64 | CNA2 | 1.97 | CNA2 |
5† | 4.8 | CNA2 | 0.9 | CNA2 | 136 | CNA2 | 2.60 | CNA2 |
6 | 4.0 | NC | 3.8 | NC | 162 | 153 | 3.97 | 3.01 |
7 | 4.0 | 2.3 | 1.9 | 2.1 | 148 | 150 | 2.94 | 4.29 |
8 | 2.5 | 45.7 | 3.3 | 2.4 | 141 | 54 | 2.70 | 0.82 |
9 | NC | NC | NC | NC | 182 | 161 | 3.39 | 2.77 |
10† | 2.8 | CNA3 | 2.0 | CNA3 | 120 | CNA3 | 2.10 | CNA3 |
11‡ | 4.0 | NS | 4.1 | NS | 148 | NS | 2.31 | NS |
12 | NC | 5.0 | NC | 1.2 | 147 | 87 | 3.85 | 3.11 |
13 | 2.3 | 2.8 | 3.8 | 3.8 | 267 | 228 | 5.06 | 4.30 |
14 | 4.8 | 5.0 | 5.1 | 5.3 | 138 | 140 | 2.22 | 3.27 |
15 | 5.0 | 25.7 | 1.4 | 0.8 | 93 | 42 | 1.24 | 0.73 |
16 | NC | NC | NC | NC | 195 | 85 | 2.84 | 1.57 |
17 | 4.3 | NS | 1.5 | NS | 137 | NS | 4.01 | NS |
18 | 36.0 | NC | 1.9 | NC | 155 | 11 | 3.57 | 0.53 |
↵2-150 Second study between 11 and 16 weeks (mean (SD) 14 (1.4)) after baseline study. †Patients did not receive intra-articular therapy after the first study. ‡Patient declined follow up. NS=not studied; NC=not completed because of patient claustrophobia; CNA=completed study though not analysed because of either: (1) inadequate synovial ROI enhancement resulting from a tissued iv injection, (2) inadequate synovial ROI image enhancement because of poor localisation of contrast within the synovial ROI throughout the dynamic image series, (3) excessive patient movement.