Table 1

Effect of GM-CSF on incidence and average clinical score of CIA1-150

GM-CSF Days Kill Incidence (n) Average clinical score
+ +
Experiment 121–25452/107/100.1 (0.1)1.3 (0.5)§
Experiment 220–23439/108/81.2 (0.3)3.4 (0.7)§
Experiment 321–24587/1010/101.4 (0.5)3.4 (0.6)§
  • 1-150 DBA/1 mice, immunised with chick CII, were given daily ip injections at different times (see Days) with either 15 μg GM-CSF (+) or vehicle (−) and the arthritis assessed by clinical score every two to three days. Day of death. The average clinical score of each mouse was determined for the period immediately following GM-CSF, or vehicle treatment, to death. Values show the mean (SEM) of these values for the groups of mice. § p < 0.05 compared with vehicle control.