Table 1

Proposed cut off points for radiological progression according to the radiographic procedure and to the risk chosen (see results section for details). For example, in a study performed using guidelines without fluoroscopy, a change over 0.73 (at the 5% risk level) will define structural progression of the disease

Cut off points for radiological progression (mm) 
risk 5%risk 10%risk 20%
Healthy volunteers
 No guidelines1.291.080.85
 Guidelines without fluoroscopy0.730.610.47
 Guidelines with fluoroscopy0.590.490.38
Knee OA patients
 Guidelines without fluoroscopy0.620.520.41