Proteins and implicated transcription factors induced by hypoxia and anoxia
| Protein | Transcription factor | Reference |
|---|---|---|
| Hypoxia induced | ||
| Xanthine oxidoreductase (XOR) | Hypoxia inducible factor (Hif-1)-like element in promoter region, NF-IL6 | 27 |
| Haem oxygenase-1 (HO-1) | Hif-1 | 38 |
| Glyceraldehyde-3-phosphate dehydrogenase | Hif-1 | 25 |
| Lactate dehydrogenase | Hif-1 | 25 |
| Erythropoietin (EPO) | Hif-1 | 25 |
| Vascular endothelial growth factor (VEGF) | Hif-1, AP-1 | 25 |
| Transforming growth factor β (TGFβ) | Hif-1, Sp-1 | 50 |
| Endothelin-1 (ET-1) | Activating protein-1(AP-1) | 51 |
| Human α2(I) collagen | AP-1, Sp-1 complex | 52 |
| TNFα, IL1, IL8, IL6 | NFκB | |
| Anoxia induced | ||
| Lactate dehydrogenasek | ? AIF | 48 |
| Cathepsin D | ? AIF | 19 |
| Cathepsin L | ? AIF | 19 |
| Endonuclease NX | ? AIF | 26 |