Mean (SEM) concentrations of collagen crosslinks (nmol/g of fresh tissue) in articular tissue of healthy controls and in patients with osteoarthritis (OA) and rheumatoid arthritis (RA)
| n=6 | Pyr | Dpyr | Pyr/Dpyr | |
| Subchondral bone | Controls | 1313 (366) | 164 (20) | 8 (2.6) |
| OA | 221 (92) | 24 (4) | 8 (4.5) | |
| RA | 139 (7) | 26 (2) | 6 (1.4) | |
| Articular cartilage | Controls | 2150 (241) | 88 (8) | 25 (1.7) |
| OA | 1570 (266) | 63 (15) | 36 (7.7) | |
| RA | 1166 (342) | 40 (5) | 29 (8.8) | |
| Synovium | Contols | 360 (50) | 32 (3) | 12 (1.2) |
| OA | 405 (81) | 25 (7) | 20 (5.2) | |
| RA | 384 (101) | 20 (4) | 18 (2.3) |