Table 2

PGE2 production by explants of rheumatoid synovium after 20 hours in culture with and without MC activation by anti-IgE. Values are given as ng/ml/100 mg tissue

Specimen noControl
values
Secretagogue treatedRelative change(x)
6746.510.81.7
6898.548.55.7
69113.832.32.3
70010.3232.2
76315.922.31.4
77026.138.91.5
  • The secretagogue treated values were significantly higher (Wilcoxon matched pairs rank test, z=2.2 : p = 0.028).