TY - JOUR T1 - Response to: ‘Correspondence on ‘Concomitant use of oral glucocorticoids and proton pump inhibitors and risk of osteoporotic fractures among patients with rheumatoid arthritis: a population-based cohort study’’ by Zheng JF - Annals of the Rheumatic Diseases JO - Ann Rheum Dis SP - e94 LP - e94 DO - 10.1136/annrheumdis-2021-219856 VL - 82 IS - 4 AU - Shahab Abtahi AU - Johanna H M Driessen AU - Andrea M Burden AU - Patrick C Souverein AU - Joop P van den Bergh AU - Tjeerd P van Staa AU - Annelies Boonen AU - Frank de Vries Y1 - 2023/04/01 UR - http://ard.bmj.com/content/82/4/e94.abstract N2 - We thank Dr Zheng for his comments on our recently published article in the Annals of the Rheumatic Diseases entitled ‘Concomitant use of oral glucocorticoids and proton pump inhibitors and risk of osteoporotic fractures among patients with rheumatoid arthritis: a population-based cohort study’.1 2 Our main goal in this study was to bring more clinical insight into the simultaneous use of these two common medications in patients with rheumatoid arthritis (RA), that is, oral glucocorticoids (GCs) and proton pump inhibitors (PPIs), using data from a large primary care database and pharmacoepidemiological methodologies.Our results showed that there was an interaction in the risk of osteoporotic (OP) fractures with concomitant use of oral GCs and PPIs in patients with RA. Based on the adjusted hazard … ER -