TY - JOUR T1 - Physician’s global assessment is often useful in SLE, but not always: the case of clinical remission JF - Annals of the Rheumatic Diseases JO - Ann Rheum Dis SP - e77 LP - e77 DO - 10.1136/annrheumdis-2020-217611 VL - 81 IS - 5 AU - Margherita Zen AU - Francesca Saccon AU - Mariele Gatto AU - Andrea Doria Y1 - 2022/05/01 UR - http://ard.bmj.com/content/81/5/e77.abstract N2 - We read with interest the paper by Aranow et al 1 where physician’s global assessment (PGA) displayed excellent inter-rater reliability, which could rely on the inclusion of highly selected lupus experts, as stated by the authors themselves. Indeed, in previous studies, PGA showed a high intra-rater and inter-rater variability,2 3 consistently with PGA being a subjective measure.The high inter-rater reliability observed by the authors is surprising considering that the timeframe for assessing disease activity significantly varied among respondents: 36.7% scored PGA over the previous 7–10 days, 36.7% over the previous month, the remainder over shorter or longer periods of time. Additionally, in almost one-third of respondents, lupus damage was considered when scoring PGA.Notably, the authors suggest that PGA should be scored after considering laboratory results, owing to a better correlation with systemic lupus erythematosus (SLE) disease activity index-2000 (SLEDAI-2K) of postlaboratory versus prelaboratory … ER -