RT Journal Article
SR Electronic
T1 Role of ultrasound for assessment of psoriatic arthritis patients with fibromyalgia
JF Annals of the Rheumatic Diseases
JO Ann Rheum Dis
FD BMJ Publishing Group Ltd and European League Against Rheumatism
SP annrheumdis-2021-220562
DO 10.1136/annrheumdis-2021-220562
A1 Ari Polachek
A1 Victoria Furer
A1 Mirna Zureik
A1 Sharon Nevo
A1 Liran Mendel
A1 David Levartovsky
A1 Jonathan Wollman
A1 Valerie Aloush
A1 Reut Tzemach
A1 Ofir Elalouf
A1 Marina Anouk
A1 Mark Berman
A1 Ilana Kaufman
A1 Or Carmi
A1 Yael Lahat
A1 Tali Eviatar
A1 Hagit Padova
A1 Hagit Sarbagil-Maman
A1 Sara Borok
A1 Adi Broyde
A1 Lihi Eder
A1 Daphna Paran
A1 Ori Elkayam
YR 2021
UL http://ard.bmj.com/content/early/2021/07/01/annrheumdis-2021-220562.abstract
AB Objective To investigate whether ultrasonography (US), as an objective imaging modality, can optimise the evaluation of disease activity in psoriatic arthritis (PsA) patients with concomitant fibromyalgia syndrome (FMS).Methods The study population included 156 consecutive PsA patients who were recruited prospectively and fulfilled the ClASsification criteria for Psoriatic ARthritis criteria. The patients underwent complete clinical evaluation including assessment of fulfilment of the 2016 fibromyalgia classification criteria. All of the patients underwent US evaluation including 52 joints, 40 tendons and 14 entheses. The US score was based on the summation of a semiquantitative score (including synovitis, tenosynovitis and enthesitis). Scoring was performed by a sonographer blinded to the clinical data. Spearman’s correlation coefficient and multivariate linear regression models were used to examine the association of FMS with clinical and the US scores.Results Forty-two patients (26.9%) with coexisting PsA and FMS were compared with 114 (73.1%) PsA patients without FMS. Patients with PsA and FMS had significantly increased scores for clinical composite indices, including non-Minimal Disease Activity, Composite Psoriatic Disease Activity Index (CPDAI), Disease Activity for Psoriatic Arthritis (DAPSA) and Psoriatic Arthritis Disease Activity Score (PASDAS) (p<0.001). In contrast, the total US score and its subcategories were similar for those with and without FMS. The total US score significantly correlated with CPDAI, DAPSA and PASDAS (p<0.001) in the PsA without FMS but not in the PsA with FMS group. FMS was significantly associated with higher clinical scores (p<0.001) but not with the US score (multivariable linear regression models).Conclusions US has significantly greater value than composite clinical scores in the assessment of disease activity in PsA patients with FMS.All data relevant to the study are included in the article or uploaded as online supplemental information.