RT Journal Article SR Electronic T1 EULAR recommendations for intra-articular therapies JF Annals of the Rheumatic Diseases JO Ann Rheum Dis FD BMJ Publishing Group Ltd and European League Against Rheumatism SP annrheumdis-2021-220266 DO 10.1136/annrheumdis-2021-220266 A1 Jacqueline Uson A1 Sebastián Cruz Rodriguez-García A1 Raul Castellanos-Moreira A1 Terence W O'Neill A1 Michael Doherty A1 Mikael Boesen A1 Hemant Pandit A1 Ingrid Möller Parera A1 Valentina Vardanyan A1 Lene Terslev A1 Willm Uwe Kampen A1 Maria-Antonietta D'Agostino A1 Francis Berenbaum A1 Elena Nikiphorou A1 Irene A Pitsillidou A1 Jenny de la Torre-Aboki A1 Loreto Carmona A1 Esperanza Naredo YR 2021 UL http://ard.bmj.com/content/early/2021/05/24/annrheumdis-2021-220266.abstract AB Objectives To establish evidence-based recommendations to guide health professionals using intra-articular therapies (IAT) in adult patients with peripheral arthropathies.Methods A multidisciplinary international task force established the objectives, users and scope and the need for background information, including systematic literature reviews) and two surveys addressed to healthcare providers and patients throughout Europe. The evidence was discussed in a face-to-face meeting, recommendations were formulated and subsequently voted for anonymously in a three-round Delphi process to obtain the final agreement. The level of evidence was assigned to each recommendation with the Oxford levels of evidence.Results Recommendations focus on practical aspects to guide health professionals before, during and after IAT in adult patients with peripheral arthropathies. Five overarching principles and 11 recommendations were established, addressing issues related to patient information, procedure and setting, accuracy, routine and special aseptic care, safety issues and precautions to be addressed in special populations, efficacy and safety of repeated joint injections, use of local anaesthetics and aftercare.Conclusion We have developed the first evidence and expert opinion-based recommendations to guide health professionals using IAT. We hope that these recommendations will be included in different educational programmes, used by patient associations and put into practice via scientific societies to help improve uniformity and quality of care when performing IAT in peripheral adult joints.