TY - JOUR T1 - Impact of Janus kinase inhibitors on the risk of cardiovascular events in patients with rheumatoid arthritis: systematic review and meta-analysis of randomised controlled trials JF - Annals of the Rheumatic Diseases JO - Ann Rheum Dis SP - e122 LP - e122 DO - 10.1136/annrheumdis-2019-215815 VL - 79 IS - 10 AU - Young Ho Lee AU - Gwan Gyu Song Y1 - 2020/10/01 UR - http://ard.bmj.com/content/79/10/e122.abstract N2 - We read with great interest the article by Xie and colleagues1 regarding the impact of Janus kinase inhibitors (Jakinibs) on the risk of cardiovascular events in patients with rheumatoid arthritis (RA). This systematic review and meta-analysis revealed no significant change in cardiovascular risks for Jakinib-treated patients with RA in a short-term perspective study. However, some methodological issues must be addressed. First, Cochran Q is the weighted sum of squares on a standardised scale, and when it is reported with low p values, it indicates heterogeneity. … ER -