RT Journal Article SR Electronic T1 On how to not misuse hierarchical clustering on principal components to define clinically meaningful patient subgroups. Response to: ‘On using machine learning algorithms to define clinical meaningful patient subgroups’ by Pinal-Fernandez and Mammen JF Annals of the Rheumatic Diseases JO Ann Rheum Dis FD BMJ Publishing Group Ltd and European League Against Rheumatism SP annrheumdis-2019-215868 DO 10.1136/annrheumdis-2019-215868 A1 Alain Meyer A1 Lionel Spielmann A1 François Séverac YR 2019 UL http://ard.bmj.com/content/early/2019/10/18/annrheumdis-2019-215868.abstract AB