TY - JOUR T1 - Gout, Hyperuricaemia and Crystal-Associated Disease Network (G-CAN) consensus statement regarding labels and definitions of disease states of gout JF - Annals of the Rheumatic Diseases JO - Ann Rheum Dis SP - 1592 LP - 1600 DO - 10.1136/annrheumdis-2019-215933 VL - 78 IS - 11 AU - David Bursill AU - William J Taylor AU - Robert Terkeltaub AU - Abhishek Abhishek AU - Alexander K So AU - Ana Beatriz Vargas-Santos AU - Angelo Lino Gaffo AU - Ann Rosenthal AU - Anne-Kathrin Tausche AU - Anthony Reginato AU - Bernhard Manger AU - Carlo Sciré AU - Carlos Pineda AU - Caroline van Durme AU - Ching-Tsai Lin AU - Congcong Yin AU - Daniel Arthur Albert AU - Edyta Biernat-Kaluza AU - Edward Roddy AU - Eliseo Pascual AU - Fabio Becce AU - Fernando Perez-Ruiz AU - Francisca Sivera AU - Frédéric Lioté AU - Georg Schett AU - George Nuki AU - Georgios Filippou AU - Geraldine McCarthy AU - Geraldo da Rocha Castelar Pinheiro AU - Hang-Korng Ea AU - Helena De Almeida Tupinambá AU - Hisashi Yamanaka AU - Hyon K Choi AU - James Mackay AU - James R ODell AU - Janitzia Vázquez Mellado AU - Jasvinder A Singh AU - John D Fitzgerald AU - Lennart T H Jacobsson AU - Leo Joosten AU - Leslie R Harrold AU - Lisa Stamp AU - Mariano Andrés AU - Marwin Gutierrez AU - Masanari Kuwabara AU - Mats Dehlin AU - Matthijs Janssen AU - Michael Doherty AU - Michael S Hershfield AU - Michael Pillinger AU - N Lawrence Edwards AU - Naomi Schlesinger AU - Nitin Kumar AU - Ole Slot AU - Sebastien Ottaviani AU - Pascal Richette AU - Paul A MacMullan AU - Peter T Chapman AU - Peter E Lipsky AU - Philip Robinson AU - Puja P Khanna AU - Rada N Gancheva AU - Rebecca Grainger AU - Richard J Johnson AU - Ritch Te Kampe AU - Robert T Keenan AU - Sara K Tedeschi AU - Seoyoung Kim AU - Sung Jae Choi AU - Theodore R Fields AU - Thomas Bardin AU - Till Uhlig AU - Tim Jansen AU - Tony Merriman AU - Tristan Pascart AU - Tuhina Neogi AU - Viola Klück AU - Worawit Louthrenoo AU - Nicola Dalbeth Y1 - 2019/11/01 UR - http://ard.bmj.com/content/78/11/1592.abstract N2 - Objective There is a lack of standardisation in the terminology used to describe gout. The aim of this project was to develop a consensus statement describing the recommended nomenclature for disease states of gout.Methods A content analysis of gout-related articles from rheumatology and general internal medicine journals published over a 5-year period identified potential disease states and the labels commonly assigned to them. Based on these findings, experts in gout were invited to participate in a Delphi exercise and face-to-face consensus meeting to reach agreement on disease state labels and definitions.Results The content analysis identified 13 unique disease states and a total of 63 unique labels. The Delphi exercise (n=76 respondents) and face-to-face meeting (n=35 attendees) established consensus agreement for eight disease state labels and definitions. The agreed labels were as follows: ‘asymptomatic hyperuricaemia’, ‘asymptomatic monosodium urate crystal deposition’, ‘asymptomatic hyperuricaemia with monosodium urate crystal deposition’, ‘gout’, ‘tophaceous gout’, ‘erosive gout’, ‘first gout flare’ and ‘recurrent gout flares’. There was consensus agreement that the label ‘gout’ should be restricted to current or prior clinically evident disease caused by monosodium urate crystal deposition (gout flare, chronic gouty arthritis or subcutaneous tophus).Conclusion Consensus agreement has been established for the labels and definitions of eight gout disease states, including ‘gout’ itself. The Gout, Hyperuricaemia and Crystal-Associated Disease Network recommends the use of these labels when describing disease states of gout in research and clinical practice. ER -