TY - JOUR T1 - Effectiveness of low-dose radiation therapy on symptoms in patients with knee osteoarthritis JF - Annals of the Rheumatic Diseases JO - Ann Rheum Dis DO - 10.1136/annrheumdis-2018-214743 SP - annrheumdis-2018-214743 AU - Xiang-Dong Wu AU - Ke-Jia Hu AU - Bing-Yan Xiang AU - Wei Huang Y1 - 2018/12/01 UR - http://ard.bmj.com/content/early/2018/12/01/annrheumdis-2018-214743.abstract N2 - We read with interest the milestone work in the Annals of the Rheumatic Diseases by Mahler and colleagues1 on the effectiveness of low-dose radiation therapy (LDRT) on symptoms in patients with knee osteoarthritis (OA). The authors have conducted a series of studies to investigate the effects of LDRT on OA, which compensate the lack of high-level evidence in the medical literature, and inevitably forcing us to re-examine the true effectiveness of LDRT on OA in real-world clinical practice.1–3 The group should be applauded for their accomplishments. In this well-designed and well-conducted randomised, double-blinded, sham-controlled trial, they found no substantial beneficial effect on symptoms and … ER -