RT Journal Article
SR Electronic
T1 Consensus-based recommendations for the management of uveitis associated with juvenile idiopathic arthritis: the SHARE initiative
JF Annals of the Rheumatic Diseases
JO Ann Rheum Dis
FD BMJ Publishing Group Ltd and European League Against Rheumatism
SP 1107
OP 1117
DO 10.1136/annrheumdis-2018-213131
VO 77
IS 8
A1 Tamas Constantin
A1 Ivan Foeldvari
A1 Jordi Anton
A1 Joke de Boer
A1 Severine Czitrom-Guillaume
A1 Clive Edelsten
A1 Raz Gepstein
A1 Arnd Heiligenhaus
A1 Clarissa A Pilkington
A1 Gabriele Simonini
A1 Yosef Uziel
A1 Sebastian J Vastert
A1 Nico M Wulffraat
A1 Anne-Mieke Haasnoot
A1 Karoline Walscheid
A1 Annamária Pálinkás
A1 Reshma Pattani
A1 Zoltán Györgyi
A1 Richárd Kozma
A1 Victor Boom
A1 Andrea Ponyi
A1 Angelo Ravelli
A1 Athimalaipet V Ramanan
YR 2018
UL http://ard.bmj.com/content/77/8/1107.abstract
AB Background In 2012, a European initiative called Single Hub and Access point for pediatric Rheumatology in Europe (SHARE) was launched to optimise and disseminate diagnostic and management regimens in Europe for children and young adults with rheumatic diseases. Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in children and uveitis is possibly its most devastating extra-articular manifestation. Evidence-based guidelines are sparse and management is mostly based on physicians’ experience. Consequently, treatment practices differ widely, within and between nations.Objectives To provide recommendations for the diagnosis and treatment of JIA-associated uveitis.Methods Recommendations were developed by an evidence-informed consensus process using the European League Against Rheumatism standard operating procedures. A committee was constituted, consisting of nine experienced paediatric rheumatologists and three experts in ophthalmology from Europe. Recommendations derived from a validated systematic literature review were evaluated by an Expert Committee and subsequently discussed at two consensus meetings using nominal group techniques. Recommendations were accepted if >80% agreement was reached (including all three ophthalmologists).Results In total, 22 recommendations were accepted (with >80% agreement among experts): 3 on diagnosis, 5 on disease activity measurements, 12 on treatment and 2 on future recommendations.Conclusions The SHARE initiative aims to identify best practices for treatment of patients suffering from JIA-associated uveitis. Within this remit, recommendations for the diagnosis and treatment of JIA-associated uveitis have been formulated by an evidence-informed consensus process to suggest a standard of care for JIA-associated uveitis patients throughout Europe.