RT Journal Article SR Electronic T1 Recommendations for the management of autoinflammatory diseases JF Annals of the Rheumatic Diseases JO Ann Rheum Dis FD BMJ Publishing Group Ltd and European League Against Rheumatism SP 1636 OP 1644 DO 10.1136/annrheumdis-2015-207546 VO 74 IS 9 A1 ter Haar, Nienke M A1 Oswald, Marlen A1 Jeyaratnam, Jerold A1 Anton, Jordi A1 Barron, Karyl S A1 Brogan, Paul A A1 Cantarini, Luca A1 Galeotti, Caroline A1 Grateau, Gilles A1 Hentgen, Veronique A1 Hofer, Michael A1 Kallinich, Tilmann A1 Kone-Paut, Isabelle A1 Lachmann, Helen J A1 Ozdogan, Huri A1 Ozen, Seza A1 Russo, Ricardo A1 Simon, Anna A1 Uziel, Yosef A1 Wouters, Carine A1 Feldman, Brian M A1 Vastert, Sebastiaan J A1 Wulffraat, Nico M A1 Benseler, Susanne M A1 Frenkel, Joost A1 Gattorno, Marco A1 Kuemmerle-Deschner, Jasmin B YR 2015 UL http://ard.bmj.com/content/74/9/1636.abstract AB Autoinflammatory diseases are characterised by fever and systemic inflammation, with potentially serious complications. Owing to the rarity of these diseases, evidence-based guidelines are lacking. In 2012, the European project Single Hub and Access point for paediatric Rheumatology in Europe (SHARE) was launched to optimise and disseminate regimens for the management of children and young adults with rheumatic diseases, facilitating the clinical practice of paediatricians and (paediatric) rheumatologists. One of the aims of SHARE was to provide evidence-based recommendations for the management of the autoinflammatory diseases cryopyrin-associated periodic syndromes (CAPS), tumour necrosis factor (TNF) receptor-associated periodic syndrome (TRAPS) and mevalonate kinase deficiency (MKD). These recommendations were developed using the European League Against Rheumatism standard operating procedure. An expert committee of paediatric and adult rheumatologists was convened. Recommendations derived from the systematic literature review were evaluated by an online survey and subsequently discussed at a consensus meeting using Nominal Group Technique. Recommendations were accepted if more than 80% agreement was reached. In total, four overarching principles, 20 recommendations on therapy and 14 recommendations on monitoring were accepted with ≥80% agreement among the experts. Topics included (but were not limited to) validated disease activity scores, therapy and items to assess in monitoring of a patient. By developing these recommendations, we aim to optimise the management of patients with CAPS, TRAPS and MKD.