RT Journal Article
SR Electronic
T1 EULAR-PReS points to consider for the use of imaging in the diagnosis and management of juvenile idiopathic arthritis in clinical practice
JF Annals of the Rheumatic Diseases
JO Ann Rheum Dis
FD BMJ Publishing Group Ltd and European League Against Rheumatism
SP 1946
OP 1957
DO 10.1136/annrheumdis-2015-207892
VO 74
IS 11
A1 A N Colebatch-Bourn
A1 C J Edwards
A1 P Collado
A1 M-A D'Agostino
A1 R Hemke
A1 S Jousse-Joulin
A1 M Maas
A1 A Martini
A1 E Naredo
A1 M Østergaard
A1 M Rooney
A1 N Tzaribachev
A1 M A van Rossum
A1 J Vojinovic
A1 P G Conaghan
A1 C Malattia
YR 2015
UL http://ard.bmj.com/content/74/11/1946.abstract
AB To develop evidence based points to consider the use of imaging in the diagnosis and management of juvenile idiopathic arthritis (JIA) in clinical practice. The task force comprised a group of paediatric rheumatologists, rheumatologists experienced in imaging, radiologists, methodologists and patients from nine countries. Eleven questions on imaging in JIA were generated using a process of discussion and consensus. Research evidence was searched systematically for each question using MEDLINE, EMBASE and Cochrane CENTRAL. Imaging modalities included were conventional radiography, ultrasound, MRI, CT, scintigraphy and positron emission tomography. The experts used the evidence obtained from the relevant studies to develop a set of points to consider. The level of agreement with each point to consider was assessed using a numerical rating scale. A total of 13 277 references were identified from the search process, from which 204 studies were included in the systematic review. Nine points to consider were produced, taking into account the heterogeneity of JIA, the lack of normative data and consequent difficulty identifying pathology. These encompassed the role of imaging in making a diagnosis of JIA, detecting and monitoring inflammation and damage, predicting outcome and response to treatment, use of guided therapies, progression and remission. Level of agreement for each proposition varied according to the research evidence and expert opinion. Nine points to consider and a related research agenda for the role of imaging in the management of JIA were developed using published evidence and expert opinion.