TY - JOUR T1 - Are autoantibodies to RNA-polymerase III to be incorporated in routine diagnostic laboratory algorithms for systemic autoimmune rheumatic diseases? JF - Annals of the Rheumatic Diseases JO - Ann Rheum Dis SP - e29 LP - e29 DO - 10.1136/annrheumdis-2014-205193 VL - 73 IS - 5 AU - Jan Damoiseaux Y1 - 2014/05/01 UR - http://ard.bmj.com/content/73/5/e29.abstract N2 - Recently a collaborative initiative of the American College of Rheumatology and the European League against Rheumatism resulted in novel classification criteria for systemic sclerosis (SSc).1 These criteria were first selected in a derivation cohort and, next, confirmed in a validation cohort. From a laboratory perspective it is interesting that the new criteria include, besides the classical anticentromere and antitopoisomerase I antibodies, also the anti-RNA polymerase III antibodies (ARA). These ARA have been associated with diffuse cutaneous involvement and … ER -