TY - JOUR T1 - Involvement of chemokines in the spontaneous ankylosis mouse model: further evidence for the ‘entheseal stress’ hypothesis JF - Annals of the Rheumatic Diseases JO - Ann Rheum Dis SP - A17 LP - A18 DO - 10.1136/ard.2010.129593f VL - 69 IS - Suppl 2 AU - K Braem AU - S Carter AU - C Deroose AU - F P Luyten AU - R J Lories Y1 - 2010/03/01 UR - http://ard.bmj.com/content/69/Suppl_2/A17.2.abstract N2 - Studies in the spontaneous ankylosis model in ageing male DBA/1 mice and in patients with ankylosing spondylitis have provided evidence that inflammation and new tissue formation leading to joint or spine ankylosis are likely to be linked but are largely uncoupled processes. We have previously proposed the ‘entheseal stress’ hypothesis that defines microdamage to the enthesis as a starting point for these murine and human diseases. To study the involvement of inflammatory pathways in … ER -