TY - JOUR T1 - Single injection of antigen-specific regulatory Tr1 lymphocytes protects mice from severe collagen-induced arthritis JF - Annals of the Rheumatic Diseases JO - Ann Rheum Dis SP - A71 LP - A71 DO - 10.1136/ard.2010.129668p VL - 69 IS - Suppl 2 AU - D Martire AU - A-L Bonnefont AU - H Asnagli AU - N Belmonte AU - M Jourdin-Boucard AU - S Rouquier AU - A Mantello AU - P B Fall AU - A Foussat AU - C Jorgensen AU - P Louis-Plence Y1 - 2010/03/01 UR - http://ard.bmj.com/content/69/Suppl_2/A71.1.abstract N2 - Tr1 cells have been characterised as induced T regulatory lymphocytes (Treg) inhibiting inflammation in various chronic inflammatory models. Based on these data, a clinical trial is ongoing in Crohn's disease. However, the therapeutic potential of these cells has not yet been evaluated in rheumatoid arthritis. Collagen type II specific … ER -