RT Journal Article
SR Electronic
T1 Thumb base involvement in symptomatic hand osteoarthritis is associated with more pain and functional disability
JF Annals of the Rheumatic Diseases
JO Ann Rheum Dis
FD BMJ Publishing Group Ltd and European League Against Rheumatism
SP 585
OP 587
DO 10.1136/ard.2009.104562
VO 69
IS 3
A1 Bijsterbosch, Jessica
A1 Visser, Willemien
A1 Kroon, Herman M
A1 Stamm, Tanja
A1 Meulenbelt, Ingrid
A1 Huizinga, Tom W J
A1 Kloppenburg, Margreet
YR 2010
UL http://ard.bmj.com/content/69/3/585.abstract
AB Objective To assess the impact of different subsets of symptomatic hand osteoarthritis (OA) on pain and disability. Methods From 308 patients with hand OA a group with carpometacarpal joint (CMCJ) symptoms only (group I, n=20) was identified as well as groups with symptoms at the interphalangeal joints (IPJs) only (group II, n=138), and symptoms at both sites (group III, n=150). Hand pain and function, assessed with the AUSCAN, were compared between groups using linear mixed models. Radiological OA was assessed using the Kellgren–Lawrence grading scale. Results Mean (SD) AUSCAN scores for groups I, II and III were 23.1 (11.7), 18.3 (11.9) and 26.4 (12.5), respectively. After adjustment for age, gender, body mass index, family effects and number of symptomatic hand joints, significant differences in AUSCAN scores of 7.4 (95% CI 1.8 to 13.0) between groups I and II, and 5.7 (95% CI 2.7 to 8.6) between groups II and III were found. AUSCAN scores were 5.8 (95% CI 3.1 to 8.6) higher for patients with versus patients without CMCJ symptoms. Kellgren–Lawrence scores did not differ between groups. Conclusion In symptomatic hand OA, CMCJ OA contributes more to pain and disability than IPJ OA. Hence, treatment of CMCJ OA should be emphasised, even if it coincides with IPJ OA.