RT Journal Article
SR Electronic
T1 Hyperuricaemia and gout: state of the art and future perspectives
JF Annals of the Rheumatic Diseases
JO Ann Rheum Dis
FD BMJ Publishing Group Ltd and European League Against Rheumatism
SP 1738
OP 1743
DO 10.1136/ard.2010.136218
VO 69
IS 10
A1 Nicola Dalbeth
A1 Alexander So
YR 2010
UL http://ard.bmj.com/content/69/10/1738.abstract
AB Major progress has been made in the past decade in understanding the pathogenesis and treatment of gout. These advances include identification of the genetic and environmental risk factors for gout, recognition that gout is an important risk factor for cardiovascular disease, elucidation of the pathways regulating the acute gout attack and the development of novel therapeutic agents to treat both the acute and chronic phases of the disease. This review summarises these advances and highlights the research agenda for the next decade.