PT  - JOURNAL ARTICLE
AU  - Nash, P
AU  - Mease, P J
AU  - Braun, J
AU  - van der Heijde, D
TI  - Seronegative spondyloarthropathies: to lump or split?
AID  - 10.1136/ard.2004.033654
DP  - 2005 Mar 01
TA  - Annals of the Rheumatic Diseases
PG  - ii9--ii13
VI  - 64
IP  - suppl 2
4099  - http://ard.bmj.com/content/64/suppl_2/ii9.short
4100  - http://ard.bmj.com/content/64/suppl_2/ii9.full
SO  - Ann Rheum Dis2005 Mar 01; 64
AB  - The advent of novel biological therapies for the treatment of rheumatic disease has renewed interest in the seronegative spondyloarthropathies (SpAs). International efforts are redefining disease classification and measures of disease activity, outcome, metrology, and imaging. However, opinion is divided between those who propose that the SpA group represents the same disease with variable expression (the “lumpers”) and those who consider these to be separate diseases with shared clinical features (the “splitters”). This review presents the evidence for both approaches.