RT Journal Article
SR Electronic
T1 Psoriatic arthritis: epidemiology, clinical features, course, and outcome
JF Annals of the Rheumatic Diseases
JO Ann Rheum Dis
FD BMJ Publishing Group Ltd and European League Against Rheumatism
SP ii14
OP ii17
DO 10.1136/ard.2004.032482
VO 64
IS suppl 2
A1 Gladman, D D
A1 Antoni, C
A1 Mease, P
A1 Clegg, D O
A1 Nash, P
YR 2005
UL http://ard.bmj.com/content/64/suppl_2/ii14.abstract
AB Psoriatic arthritis (PsA) has been defined as a unique inflammatory arthritis associated with psoriasis. Its exact prevalence is unknown, but estimates vary from 0.3% to 1% of the population. The clinical features described initially are recognised by most experienced clinicians, although they are most distinct in early disease. Initially, PsA typically presents as an oligoarticular and mild disease. However, with time PsA becomes polyarticular, and it is a severe disease in at least 20% of patients. Patients with PsA who present with polyarticular disease are at risk for disease progression. In addition to progression of clinical and radiological damage, health related quality of life is reduced among patients with PsA. It important to note that patients included in recent drug trials resemble patients followed prospectively in a clinic.