PT - JOURNAL ARTICLE AU - Landewé, R AU - van der Heijde, D TI - Presentation and analysis of radiographic data in clinical trials and observational studies AID - 10.1136/ard.2005.042572 DP - 2005 Nov 01 TA - Annals of the Rheumatic Diseases PG - iv48--iv51 VI - 64 IP - suppl 4 4099 - http://ard.bmj.com/content/64/suppl_4/iv48.short 4100 - http://ard.bmj.com/content/64/suppl_4/iv48.full SO - Ann Rheum Dis2005 Nov 01; 64 AB - Despite the advent of sophisticated imaging systems, plain radiography continues to be a valuable outcome variable in clinical trials of inflammatory disorders for a number of reasons. This paper discusses the pros and cons of the different ways in which radiographic data in trials is presented; the minimum time needed to demonstrate radiographic progression in the context of a clinical trial; and the best ways to statistically analyse radiographic data.