RT Journal Article
SR Electronic
T1 Is progressive osteoarthritis an atheromatous vascular disease?
JF Annals of the Rheumatic Diseases
JO Ann Rheum Dis
FD BMJ Publishing Group Ltd and European League Against Rheumatism
SP 1539
OP 1541
DO 10.1136/ard.2005.039263
VO 64
IS 11
A1 P G Conaghan
A1 H Vanharanta
A1 P A Dieppe
YR 2005
UL http://ard.bmj.com/content/64/11/1539.abstract
AB Growing evidence from epidemiological studies suggests that osteoarthritis (OA) is linked to atheromatous vascular disease. This hypothesis article proposes that OA, or at least OA structural progression, may be an atheromatous vascular disease of subchondral bone. Further epidemiological studies, imaging investigations of relevant blood vessels, and trials of the effects of statins on the prevention and treatment of OA are needed to examine this hypothesis.