PT - JOURNAL ARTICLE AU - P G Conaghan AU - H Vanharanta AU - P A Dieppe TI - Is progressive osteoarthritis an atheromatous vascular disease? AID - 10.1136/ard.2005.039263 DP - 2005 Nov 01 TA - Annals of the Rheumatic Diseases PG - 1539--1541 VI - 64 IP - 11 4099 - http://ard.bmj.com/content/64/11/1539.short 4100 - http://ard.bmj.com/content/64/11/1539.full SO - Ann Rheum Dis2005 Nov 01; 64 AB - Growing evidence from epidemiological studies suggests that osteoarthritis (OA) is linked to atheromatous vascular disease. This hypothesis article proposes that OA, or at least OA structural progression, may be an atheromatous vascular disease of subchondral bone. Further epidemiological studies, imaging investigations of relevant blood vessels, and trials of the effects of statins on the prevention and treatment of OA are needed to examine this hypothesis.