RT Journal Article
SR Electronic
T1 Adhesion molecules in rheumatoid arthritis: role in the pathogenesis and prospects for therapy.
JF Annals of the Rheumatic Diseases
JO Ann Rheum Dis
FD BMJ Publishing Group Ltd and European League Against Rheumatism
SP 287
OP 288
DO 10.1136/ard.53.5.287
VO 53
IS 5
A1 C Pitzalis
A1 G Kingsley
A1 G Panayi
YR 1994
UL http://ard.bmj.com/content/53/5/287.abstract
AB The essential role played by cell adhesion and migration in the generation of chronic synovitis is now beyond doubt. Some of the beneficial effects of currently used drugs may be related to their ability to interfere with these mechanisms. The complexity of the process, however, means that there are many potential targets for therapeutic intervention and therefore further studies of the basic mechanisms are necessary to identify those which are most important.