RT Journal Article SR Electronic T1 Systemic amyloidosis AL with temporal artery involvement revealing lymphoplasmacytic malignancy in a man presenting as polymyalgia rheumatica. JF Annals of the Rheumatic Diseases JO Ann Rheum Dis FD BMJ Publishing Group Ltd and European League Against Rheumatism SP 158 OP 160 DO 10.1136/ard.52.2.158 VO 52 IS 2 A1 P Lafforgue A1 E Senbel A1 D Figarella-Branger A1 J Boucraut A1 N Horschowsky A1 J F Pellissier A1 P C Acquaviva YR 1993 UL http://ard.bmj.com/content/52/2/158.abstract AB A 68 year old man presented with a clinical and biological picture that suggested polymyalgia rheumatica. Temporal artery biopsy disclosed no inflammatory change but massive light chain amyloid deposits in the media. Further exploration showed a malignant lymphoplasmacytic haemopathy with a triclonal gammopathy and a muscular, rectal, and probable cardiac amyloidosis. Cryoglobulinaemia and high concentrations of soluble interleukin 2 receptor (sIL-2R) were also found. This is the fifth case with confirmed involvement of the temporal artery. The especially high sIL-2R concentration was thought to reflect the tumour mass rather than lymphocyte activation.