TY - JOUR T1 - Systemic amyloidosis AL with temporal artery involvement revealing lymphoplasmacytic malignancy in a man presenting as polymyalgia rheumatica. JF - Annals of the Rheumatic Diseases JO - Ann Rheum Dis SP - 158 LP - 160 DO - 10.1136/ard.52.2.158 VL - 52 IS - 2 AU - P Lafforgue AU - E Senbel AU - D Figarella-Branger AU - J Boucraut AU - N Horschowsky AU - J F Pellissier AU - P C Acquaviva Y1 - 1993/02/01 UR - http://ard.bmj.com/content/52/2/158.abstract N2 - A 68 year old man presented with a clinical and biological picture that suggested polymyalgia rheumatica. Temporal artery biopsy disclosed no inflammatory change but massive light chain amyloid deposits in the media. Further exploration showed a malignant lymphoplasmacytic haemopathy with a triclonal gammopathy and a muscular, rectal, and probable cardiac amyloidosis. Cryoglobulinaemia and high concentrations of soluble interleukin 2 receptor (sIL-2R) were also found. This is the fifth case with confirmed involvement of the temporal artery. The especially high sIL-2R concentration was thought to reflect the tumour mass rather than lymphocyte activation. ER -