@article {Lafforgue158, author = {P Lafforgue and E Senbel and D Figarella-Branger and J Boucraut and N Horschowsky and J F Pellissier and P C Acquaviva}, title = {Systemic amyloidosis AL with temporal artery involvement revealing lymphoplasmacytic malignancy in a man presenting as polymyalgia rheumatica.}, volume = {52}, number = {2}, pages = {158--160}, year = {1993}, doi = {10.1136/ard.52.2.158}, publisher = {BMJ Publishing Group Ltd}, abstract = {A 68 year old man presented with a clinical and biological picture that suggested polymyalgia rheumatica. Temporal artery biopsy disclosed no inflammatory change but massive light chain amyloid deposits in the media. Further exploration showed a malignant lymphoplasmacytic haemopathy with a triclonal gammopathy and a muscular, rectal, and probable cardiac amyloidosis. Cryoglobulinaemia and high concentrations of soluble interleukin 2 receptor (sIL-2R) were also found. This is the fifth case with confirmed involvement of the temporal artery. The especially high sIL-2R concentration was thought to reflect the tumour mass rather than lymphocyte activation.}, issn = {0003-4967}, URL = {https://ard.bmj.com/content/52/2/158}, eprint = {https://ard.bmj.com/content/52/2/158.full.pdf}, journal = {Annals of the Rheumatic Diseases} }