RT Journal Article
SR Electronic
T1 Cutaneous vasculitis and IgA glomerulonephritis in ankylosing spondylitis.
JF Annals of the Rheumatic Diseases
JO Ann Rheum Dis
FD BMJ Publishing Group Ltd and European League Against Rheumatism
SP 61
OP 62
DO 10.1136/ard.52.1.61
VO 52
IS 1
A1 C Beauvais
A1 G Kaplan
A1 B Mougenot
A1 C Michel
A1 E Marinho
YR 1993
UL http://ard.bmj.com/content/52/1/61.abstract
AB Two patients with ankylosing spondylitis were found to have IgA nephropathy and leucocytoclastic cutaneous vasculitis. Immunofluorescence showed perivascular deposition of IgA in the skin of one patient and in the mesangium of both patients. Such an association has been reported only once before. This supports the concept of abnormal IgA immune stimulation in the pathogenesis of ankylosing spondylitis.