RT Journal Article
SR Electronic
T1 Possible induction of systemic lupus erythematosus by human parvovirus.
JF Annals of the Rheumatic Diseases
JO Ann Rheum Dis
FD BMJ Publishing Group Ltd and European League Against Rheumatism
SP 803
OP 804
DO 10.1136/ard.51.6.803
VO 51
IS 6
A1 A P Cope
A1 A Jones
A1 M Brozovic
A1 M S Shafi
A1 R N Maini
YR 1992
UL http://ard.bmj.com/content/51/6/803.abstract
AB A 59 year old woman presented with an influenza-like illness preceding signs and symptoms strongly suggestive of systemic lupus erythematosus (SLE), which progressed over several months. Owing to these influenza-like symptoms, a viral cause of her illness was sought. Human parvovirus B19 serology was positive and antibodies to DNA were detected by two different methods. This patient is believed to be the first report of human parvovirus B19 infection coinciding with the onset of SLE. The evidence for B19 virus and the part it plays in autoimmunity and arthritis is discussed.